Exploring the science.

It doesn’t have to be scary. Learn about the latest research findings and discover why Kambo is trusted by practitioners worldwide.

Acute and subacute psychoactive effects of Kambo

Our study reveals distinct differences between the acute effects of Kambo and those of serotonergic psychedelics. While Kambo induces strong physical reactions followed by increased introspection, psychedelics typically promote ego dissolution and enhanced connectedness. However, both Kambo and psychedelics share similarities in subacute effects, including increased energy, mental clarity, and an 'afterglow' sensation. This suggests that while Kambo may not induce psychedelic states, it can still produce transformative and transpersonal effects akin to those of psychedelics.

 

Review of the physiological effects of phyllomedusa bicolor skin secretion on humans

Several peptides found in Kambo hold promise for medicinal use, with potential synergistic effects when combined. Despite anecdotal reports of benefits, controlled studies on humans assessing Kambo's physiological and psychological effects are lacking. Further research is needed to understand the complex peptide mixture's effects, dosage standardization, and placebo influence. With Kambo's growing popularity, urgent clinical research is essential to evaluate its safety and therapeutic potential, ensuring public safety and promoting medical advancement.

 

Use of phyllomedusa bicolor secretion during kambo ritual

Observational responses, dosage and risk of adverse events

While Kambo administration showed varied responses influenced by factors like point number and location, no severe adverse effects were observed in the studied sample, likely due to careful risk management and facilitator supervision. However, the increasing popularity of Kambo calls for heightened clinician awareness regarding associated risks.

 

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